Turn-on Research Articles

Gut microbiota is involved in male reproductive function: a review

Globally, ~8%−12% of couples confront infertility issues, male-related issues being accountable for 50%. This review focuses on the influence of gut microbiota and their metabolites on the male reproductive system from five perspectives: sperm quality, testicular structure, sex hormones, sexual behavior, and probiotic supplementation. To improve sperm quality, gut microbiota can secrete metabolites by themselves or regulate host metabolites. Endotoxemia is a key factor in testicular structure damage that causes orchitis and disrupts the blood-testis barrier (BTB). In addition, the gut microbiota can regulate sex hormone levels by participating in the synthesis of sex hormone-related enzymes directly and participating in the enterohepatic circulation of sex hormones, and affect the hypothalamic-pituitary-testis (HPT) axis. They can also activate areas of the brain that control sexual arousal and behavior through metabolites. Probiotic supplementation can improve male reproductive function. Therefore, the gut microbiota may affect male reproductive function and behavior; however, further research is needed to better understand the mechanisms underlying microbiota-mediated male infertility.

Validity and Reliability Evidence and Norms for the Spanish Version of the Sexual Inhibition/Sexual Excitation Scales-Short Form.

The Sexual Inhibition/Sexual Excitation Scales-Short Form (SIS/SES-SF) is a brief instrument for assessing the propensity for sexual excitement and inhibition in men and women. The aim of the present study was to provide evidence for the validity and reliability of the Spanish version of the SIS/SES-SF scores by examining invariance, reliability (information function and internal consistency), the relationship between the scores and sexual functioning, and presenting its standard scores. A total of 2,223 Spanish heterosexuals (43.41% men and 56.59% women) aged 18 to 83 years (M = 39.94, SD = 11.95), distributed across age groups (18-34, 35-49, ≥ 50 years old) participated. The three-factor structure of the Spanish version of SIS/SES-SF showed weak measurement invariance by sex and strict measurement invariance by age. The scores explained the dimensions of sexual functioning, especially sexual arousal and erection/lubrication. In addition, men and women without difficulties in sexual functioning demonstrated more propensity for sexual excitation and less sexual inhibition. The standard scores are presented by sex and age group. The study provides evidence of the validity and reliability of the SIS/SES-SF measures, confirming its usefulness for assessing propensity to sexual excitation and inhibition.

Structural Relationships of Sexual Inhibition and Sexual Excitation with Female Sexual Function: The Mediating Role of Sexually Dysfunctional Beliefs

Background: Sexual function is a critical aspect of human life, significantly impacting mental and physical health, social behavior, and quality of life. Objectives: This study aimed to investigate the structural relationships among sexual inhibition (SI), sexual excitation (SE), sexual dysfunctional beliefs, and female sexual function. Methods: Employing a descriptive correlational design, the study administered questionnaires to 402 female employees in the administrative departments of Tehran and Tabriz universities, utilizing convenience sampling. The instruments included the Female Sexual Function Index (FSFI), Sexual Inhibition and Sexual Excitation Questionnaire (SISE-W), and Sexual Dysfunctional Beliefs Questionnaire (SDBQ). Data analysis was conducted using SPSS version 24 and Lisrel version 8.8 software. Results: Our findings revealed that SE related to FSFI both directly (B = 0.29; P < 0.01) and through the mediating role of sexual dysfunction beliefs. However, SI did not exhibit a direct relationship with FSFI (B = -0.07; P > 0.05). Additionally, sexual dysfunction beliefs significantly predicted FSFI (B = -0.40; P < 0.01). The assumed model demonstrated good fit with the acquired data (CFI = 0.98, NFI = 0.96, RFI = 0.95, RMSEA = 0.08). Conclusions: Therefore, it can be concluded that sexually dysfunctional beliefs play a mediating role in the correlation between inhibition, SE, and female sexual function.

Research in brief: How prevalent is rough sex? Results from a national online sample of adults in Germany.

Rough sex refers to consensual sexual activities that incorporate playful aggression, such as hair pulling, spanking, or choking. It is relevant in the context of sexual health as it can enhance sexual arousal, pleasure, and intimacy among consenting partners. However, it can also be associated with consent violations, discomfort, and injuries ranging from mild to severe or even fatal. The prevalence of rough sex in Germany is widely unknown. Our study aims to establish, for the first time, the overall age-related and gender-related prevalence rates of active and passive rough sex involvement among adults in Germany. A national online sample of 1101 adults from Germany, aged 18-69 years (50% men, 49% women, 1% gender-diverse individuals) gave informed consent and reported on their lifetime engagement in rough sex in active and passive roles. We recruited participants through a professional panel provider for a multi-themed sexual health survey. Data analysis was conducted using R, with 95% confidence intervals of prevalence rates computed to answer the research questions. Lifetime prevalence of rough sex involvement was 29%. Adults below the age of 40 reported higher rates of involvement (up to 43%) than people over 40 (up to 26%). Men reported predominantly active role involvement and women reported primarily passive role involvement. Results show that rough sex is common. Sexual health professionals, educators, and researchers should be prepared to guide current and aspiring practitioners of rough sex, helping them understand potential benefits, risks, and age- and gender-related differences.

The characteristics of sexual behavior in blind men in Ganzhou, China: A cross-sectional study.

Visual stimuli play key roles in influencing men sexual behavior. However, few studies have explored the sexual behavior of blind men. To provide more information about blind men for the study of andrology by surveying the characteristics of their current sexual behavior. A questionnaire-based cross-sectional study design was performed. The questionnaire contained questions regarding demographic characteristics of participants, access to sexual knowledge, perception of the sexual partners' beauty, and sexual arousal. Blind men were interviewed face-to-face by the trained investigator. Complete questionnaires were collected from 54 participants, with an average age of 40.57 ± 9.80 years old. Eye diseases were the most frequent cause of blindness. In terms of sexual orientation, all participants were heterosexual. Notably, 90.7% of the participants reported to have had a sexual experience. Among those who had engaged in sexual behavior, 93.6% experienced sexual pleasure and 69.4% had a normal erectile function. Overall, 16.7% of the participants received sex education. The participants obtained sexual knowledge mainly through sounds from mobile phones, peer-to-peer communication, sounds of television and radio. Voice was the most frequent perception of the sexual partners' beauty, followed by figure, skin, and body fragrance. In terms of stimuli of sexual arousal, tactile sensation and auditory sensation in that order were the most frequent stimuli of sexual arousal. Stimuli of sexual arousal in blind men are mainly mediated by sound and touch. Blind men understand their sexual partners' beauty through auditory, tactile, and olfactory sensations. Blind men in Ganzhou lack formal and systematic sex education.

[Priapism].

Priapism is defined as penile erection lasting more than four hours that is unrelated to sexual arousal. Priapism is classified based on the oxygenation of the penile tissue into ischemic and non-ischemic subtypes. As the most common form, ischemic priapism is usually associated with pain and carries asignificant risk of permanent loss of erectile function; thus, rapid intervention is necessary. Initial therapy consists of corporal aspiration and injection of sympathomimetic agents. If detumescence is not achieved, acavernosal shunt is necessary. Non-ischemic priapism is less common than the ischemic type and is usually the result of perineal trauma. In this subtype, there is usually no pain and treatment is initially conservative. Recurrent (stuttering) priapism is avariant of the ischemic subtype, but is self-limiting and usually occurs during sleep with aduration of less than three to four hours. In the case of prolonged erection, therapy is analogous to that of the ischemic subtype.

Does Near Miss Compromise Sexual Function in Reproductive-Aged Women? A Comparative Cross-Sectional Study in Ahvaz, Iran

Background: Maternal near miss (MNM) is defined as any life-threatening event during pregnancy, delivery, or within six weeks after the termination of pregnancy. Objectives: This cross-sectional study aimed to assess sexual function in women with (n = 140) and without MNM (n = 246). Methods: Eligible participants were women with MNM and basic literacy who had given birth at least 8 - 12 weeks prior to the study. Participants were recruited from Imam Khomeini and Taleghani hospitals, while women without MNM were recruited from two public health centers in Ahvaz. Data collection commenced in December 2020 and concluded in March 2021. A demographic questionnaire and the Female Sexual Function Index were used to collect the data. Data were analyzed using independent t-tests, chi-square tests, and multiple linear regression. Results: The predominant mode of delivery among MNM women was cesarean section (70%, P < 0.05). The most common causes of MNM were preeclampsia (41.43%) and placenta accreta (24.29%), followed by hypertension and diabetes (17.86%). Women without MNM reported significantly higher scores in sexual satisfaction (β = 0.355, 95% CI: 0.019, 0.690, P = 0.035), lubrication (β = 0.707, 95% CI: 0.435, 0.980, P < 0.0001), sexual arousal (β = 0.394, 95% CI: 0.116, 0.522, P = 0.007), sexual desire (β = 0.319, 95% CI: 0.116, 0.522, p = 0.002), and total sexual function score (β = 1.768, 95% CI: 0.306, 3.230, P = 0.018). Women who had undergone cesarean section reported lower scores in sexual satisfaction (β = -0.646, 95% CI: -0.983, -0.309, P < 0.0001), orgasm (β = -0.620, 95% CI: -0.965, -0.275, P < 0.0001), sexual arousal (β = -0.473, 95% CI: 0.159, 0.439, P = 0.001), and total sexual function score (β = -3.181, 95% CI: -4.655, -1.707, P < 0.0001). Older women scored significantly lower in all components of sexual function except for pain. Conclusions: The study results indicated that all components of sexual function, except pain, were lower in women with MNM. A significantly higher number of women who had undergone cesarean section experienced MNM and sexual dysfunction. Health policymakers should focus not only on the causes of MNM, particularly cesarean sections, but also on assessing the sexual function of women affected by MNM.

Emotion Classification Based on Pulsatile Images Extracted from Short Facial Videos via Deep Learning.

Most human emotion recognition methods largely depend on classifying stereotypical facial expressions that represent emotions. However, such facial expressions do not necessarily correspond to actual emotional states and may correspond to communicative intentions. In other cases, emotions are hidden, cannot be expressed, or may have lower arousal manifested by less pronounced facial expressions, as may occur during passive video viewing. This study improves an emotion classification approach developed in a previous study, which classifies emotions remotely without relying on stereotypical facial expressions or contact-based methods, using short facial video data. In this approach, we desire to remotely sense transdermal cardiovascular spatiotemporal facial patterns associated with different emotional states and analyze this data via machine learning. In this paper, we propose several improvements, which include a better remote heart rate estimation via a preliminary skin segmentation, improvement of the heartbeat peaks and troughs detection process, and obtaining a better emotion classification accuracy by employing an appropriate deep learning classifier using an RGB camera input only with data. We used the dataset obtained in the previous study, which contains facial videos of 110 participants who passively viewed 150 short videos that elicited the following five emotion types: amusement, disgust, fear, sexual arousal, and no emotion, while three cameras with different wavelength sensitivities (visible spectrum, near-infrared, and longwave infrared) recorded them simultaneously. From the short facial videos, we extracted unique high-resolution spatiotemporal, physiologically affected features and examined them as input features with different deep-learning approaches. An EfficientNet-B0 model type was able to classify participants' emotional states with an overall average accuracy of 47.36% using a single input spatiotemporal feature map obtained from a regular RGB camera.

Sexual dysfunction among Nigerian women living with HIV infection.

Sexual dysfunction in women with HIV is a necessary but understudied aspect of HIV complications in women living with HIV. This study reports the prevalence, pattern, and risk factors for sexual dysfunction in women living with HIV in southwest Nigeria. A validated Female Sexual Function Index was used to determine sexual dysfunction in a cross-sectional study design involving 2926 adult women living with HIV in a large, publicly funded tertiary HIV treatment centre in Lagos, Nigeria. A score of less than 26.5 indicated sexual dysfunction. Multivariate logistic regression analysis was performed to identify risk factors for sexual dysfunction. P<0.05 was considered statistically significant at a 95% confidence interval (CI). The prevalence of sexual dysfunction was 71.4%. The types of dysfunctions detected included disorder of desire (76.8%), sexual arousal (66.0%), orgasm (50.0%), pain (47.2%), lubrication (47.2%), and satisfaction (38.8%). Multivariate analysis showed that menopause (aOR: 2.0; 1.4-4.1), PHQ score of 10 and above (aOR: 2.3; 1.7-3.2), co-morbid medical conditions (aOR: 1.8; 1.4-2.7), use of protease inhibitor-based antiretroviral therapy (aOR: 1.3; 1.2-2.1) and non-disclosure of HIV status (aOR: 0.7; 0.6-0.8) were factors associated with sexual dysfunction. Sexual dysfunction is common among Nigerian women living with HIV. Menopause, use of protease inhibitor-based regimens, PHQ score of at least 10, co-morbid medical condition, and non-disclosure of HIV status were associated with sexual dysfunction. National HIV programmes, in addition to incorporating screening and management of sexual dysfunction in the guidelines, should sensitise and train health workers on the detection and treatment of sexual dysfunction.

Evaluation of selective-serotonin reuptake inhibitors and anti-androgens to manage sexual compulsivity in individuals serving a custodial sentence for a sexual offence

ABSTRACT The UK prison system offers a medical treatment pathway for people suffering from problematic sexual arousal (PSA) who have committed a sexual offence(s). The two main medications are Anti-androgens (AAs) and Selective-Serotonin Reuptake Inhibitors (SSRIs). Currently, evidence of the effectiveness of SSRIs is not sufficiently robust for them to be licensed in the UK for that purpose. Instead, SSRIs are prescribed ‘off-label’, and physicians must adhere to additional obligations in prescribing them. Yet SSRIs have fewer side effects than AAs and may be a better treatment option for many patients. The present study examined the effectiveness of AAs and SSRIs in incarcerated individuals with PSA (n = 77); the unmedicated comparison group (n = 58) resided at the same prison which houses people convicted of a sexual offence. Both medicated groups demonstrated reduced levels of PSA 3 months post-baseline; the comparison group did not. The findings provide evidence for the effectiveness of SSRIs in reducing PSA. The authors argue a randomised control trial is required to underpin the use of SSRIs in treating PSA and (potentially) its subsequent licensing. The latter would enable wider prescription in prison and community and make a substantive contribution to the prevention of sexual abuse.

Representation Gap in Standardized Affective Stimuli Sets: A Systematic Literature Review of Visual Sexual Stimuli

AbstractVisual sexual stimuli (VSS) are often used to induce affective responses in experimental research, but can also be useful in the assessment and treatment of sexual disorders (e.g., sexual arousal dysfunctions, paraphilic disorders, compulsive sexual behaviors). This systematic literature review of standardized sets containing VSS was conducted by searching electronic databases (PsycINFO, PubMed, Scopus, Web of Science) from January 1999 to December 2022 for specific keywords [("picture set" OR "picture database" OR "video set" OR "video database" OR "visual set" OR "visual database") AND ("erotic stimuli" OR "sexual stimuli" OR "explicit erotic stimuli" OR "explicit sexual stimuli")]. Selected sets were narratively summarized according to VSS (modality, duration, explicitness, shown sexes, sexual practices, physical properties, emotion models, affective ratings) and participants’ characteristics (gender, sexual orientation and sexual preferences, cultural and ethnic diversity). Among the 20 sets included, researchers can select from ~ 1,390 VSS (85.6% images, 14.4% videos). Most sets contain VSS of opposite- and some of same-sex couples, but rarely display diverse sexual practices. Although sexual orientation and preferences strongly influence the evaluation of VSS, little consideration of both factors has been given. There was little representation of historically underrepresented cultural and ethnic groups. Therefore, our review suggests limitations and room for improvement related to the representation of gender, sexual orientation, sexual preferences, and especially cultural and ethnic diversity. Perceived shortcomings in experimental research using VSS are highlighted, and recommendations are discussed for representative stimuli for conducting and evaluating sexual affective responses in laboratory and clinical contexts while increasing the replicability of such findings.

Bipolar I disorder and anxiety disorder with spontaneous ejaculations

Anxiety and ejaculation share similar sympathetic neuronal pathways and hence they may coincide. In this case report, we describe a 30-year-old male with ongoing perceptual disturbances and spontaneous ejaculations that occur without sexual arousal. The patient ultimately benefited from pharmacological therapy with risperidone.

"One a Day Keeps the Prison Away": Understanding the Experiences of Individuals Convicted of Sexual Offences Receiving Anti-Androgens for the Treatment of Problematic Sexual Arousal.

Problematic sexual arousal (PSA) is an umbrella term to describe a range of clinical presentations related to excessive sexual thinking (e.g., sexual preoccupation) and sexual behavior (e.g., hypersexuality). Although such concepts are known to affect sexual recidivism among individuals convicted of sexual offences, PSA is not routinely or directly targeted in offending behavior programs in England and Wales. However, in recent years, there have been moves to incorporate pharmacological interventions for addressing this among people with sexual offence histories. Although some work to understand the experiences of those taking SSRI medication for this purpose has emerged, little is known about the experiences of service users taking anti-androgen medication. In this study, we interviewed all individuals in prison taking anti-androgens for the treatment of problematic sexual arousal following convictions for sexual offences in England at the time of data collection (N = 10). Using a phenomenologically oriented thematic analysis, we established themes pertaining to "Differing needs: Motivations for treatment," "Medication as a risk management strategy," and how the medication helped the men in their pursuit of "Discovering a 'new me'." This work contributes important knowledge to inform the development of ethical and effective prescribing of anti-androgen medication with this population and offer recommendations for both future research and the development of clinical practice.

The Structure of Hypersexuality and Its Relation to Impulsivity.

Among the multiple controversies surrounding hypersexuality is the important issue of whether it constitutes a univocal construct. Although an initial study supported its homogeneity, more resent research has identified two separate subcomponents-problematic sexuality and sexual drive. The present survey study addressed this issue in a sample that included both in-person tested college students (n = 69) and online respondents (n = 339). A factor analysis of scales attempting to capture the indicators of each subcomponent of hypersexuality yielded two correlated, but separate factors. Whereas Problematic Sexuality (PS) comprised scales measuring sexual compulsivity, using sex as a coping mechanism, and the negative consequences of sexual behavior, Sexual Drive (SD) was defined by frequent sexual activity, preoccupation with sexual fantasies, a predilection for impersonal sexual behavior, and facile sexual arousal. These two subcomponents of hypersexuality were found to covary with different types of impulsivity, further supporting their discrimination and providing external validation for their differentiation. Contrary to a priori hypotheses, however, PS correlated highly with Callous/Manipulative/Risk-Taking as well as with a predicted Affective Instability/Behavioral Disinhibition factor, suggesting that PS may constitute an equifinality of separate developmental trajectories for those high on both subtypes of hypersexuality.

Genital arousal and responsive desire among women with and without sexual interest/arousal disorder symptoms.

Models depicting sexual desire as responsive to sexual arousal may be particularly apt for women experiencing arousal or desire difficulties, and the degree to which arousal triggers desire may depend on the relationship context and desire target and timing-yet, these associations have not been directly tested among women with and without sexual interest/arousal disorder (SIAD). To assess the role of SIAD status and relationship satisfaction in the associations between genital arousal and 4 types of responsive desire. One hundred women (n = 27 meeting diagnostic criteria for SIAD) in romantic relationships with men viewed a sexual film (pleasurable intimate depiction of oral sex and penile-vaginal intercourse) while their genital arousal was recorded via vaginal photoplethysmography (n = 63) or thermal imaging of the labia (n = 37). Partner and solitary desire was assessed immediately before and after the film (immediate desire) and 3days later (delayed desire). Outcomes consisted of genital response (z scored by method) and associations between genital response and responsive sexual desire. The key difference between women with and without SIAD was not in their ability to experience genital arousal but in how their genital responses translated to responsive sexual desire. Women with SIAD actually exhibited greater genital arousal than unaffected women. Associations between genital arousal and desire were significant only for women with SIAD and depended on relationship satisfaction and desire type. For women with SIAD with low relationship satisfaction, higher arousal predicted lower immediate desire for a partner; for those with high relationship satisfaction, arousal was either positively related (vaginal photoplethysmography) or unrelated (thermal imaging of the labia) to immediate desire for a partner. Associations with other desire types were not significant. Patterns of genital arousal and partner-specific responsive desire among women affected with SIAD were indicative of an avoidance model in response to heightened genital arousal, unless relationship satisfaction was high; attending to genital arousal sensations could be a means of triggering sexual desire for women with SIAD who are satisfied in their relationships. This is one of the first sexual psychophysiologic studies to connect relationship factors to patterns of sexual response. The differing arousal assessment procedures and lack of official diagnosis may have attenuated results. The homogeneous sample and in-person session requirement limit generalizability. When compared with unaffected women, women affected by SIAD may exhibit stronger arousal responses with sufficiently incentivized sexual stimuli, and the connection between their genital arousal and responsive desire for their partners may be stronger and more dependent on relationship context.

Self-esteem, depression, anxiety and sexual function in Mayer-Rokitansky-Küster-Hauser syndrome with neovagina: A case series

BackgroundThe Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome is a rare condition with significant psychological implications. However, our understanding of its impact on postoperative sexual function and mental health is still limited. AimEvaluate the mental health status and sexual functioning of women with MRKH syndrome after vaginoplasty surgery. MethodsWe enrolled 53 cases with MRKH syndrome who underwent artificial vaginoplasty. The participants were asked to participate in a two-round survey conducted between February 2021 during the covid-19 period and March 2023. The survey included questionnaires to measure depression, anxiety, self-esteem, and sexual functioning. Differences between scores over time were analysed using a paired sample t-test, and we assessed the correlation between mental health and sexual functioning. ResultsIn the first round, patients’ mean ± SD age at surgery was 23.6 ± 4.5 years old, and the mean ± SD time that had elapsed since surgery at the time of the survey was 34.2 ± 20.8 months. None of the patients reported low self-esteem, 45.3 % reported mild-to-moderate depression, and 34.0 % reported mild anxiety. Thirty patients have had vaginal intercourse during the last six months. The mean ± SD Female Sexual Functioning Index score was 24.6 ± 4.4, and 60.0 % had a score of 23.5 or higher, indicating high sexual functioning. The sexual functioning scores were positively correlated with self-esteem scores and negatively correlated with depression or anxiety scores (p < 0.05). There was no significant improvement in patient's mental health status and sexual function between the second round survey (71.3 ± 17.8 months after surgery) and the first round survey (p > 0.05). In contrast, the sexual arousal of FSFI were significantly higher in the second survey round (p < 0.05). ConclusionMost patients undergoing vaginoplasty reported persisting mental health challenges. However, the majority reported good sexual functioning.

Role of kisspeptin in female and male reproduction

Kisspeptin is a neuropeptide responsible for controlling the synthesis of gonadotropin-releasing hormone (GnRH), luteinizing hormone (LH), and follicle-stimulating hormone (FSH). The G-protein-coupled receptor 54/kisspeptin 1 receptor (GPR54/KISS1R) is involved in its action. The comprehension of kisspeptin and its actions represents a significant breakthrough in the field of reproductive biology. Kisspeptins play a crucial role in the development and optimal functioning of the reproductive system in both female and male. Additionally, it contributes to the onset of puberty, regulating feedback processes, and influencing sexual desire and arousal. It regulates a number of reproductive functions in women, including ovulation, lactation, ovarian development, follicle development, oocyte maturation, and pregnancy via the hypothalamic-pituitary-gonadal (HPG) axis. Spermatogenesis, sperm function, Leydig cells, and reproductive behaviour are all impacted by it in men. Infertility and polycystic ovarian syndrome (PCOS) are among the diseases linked to kisspeptin dysregulation, according to the research. For potential future use in diagnosing and treating problems, it may be helpful to understand the mechanisms behind kisspeptin's effects on the reproductive system. This review focuses on the regulatory function of kisspeptin on the HPG axis and the impact of kisspeptin on reproductive processes in both female and male.

Adolescents’ Preferences for Mainstream and Paraphilic Pornography and Sexual Health Components: Attention to Within-And Between-Person Dynamics Over Time

ABSTRACT Health communication scholars are becoming increasingly cognizant of the potential health implications of youths’ pornography consumption. However, while research on pornography viewing and adolescent health and development has become increasingly common, the possible importance of distinguishing between mainstream and paraphilic consumption and within-and-between person dynamics has been underemphasized. Accordingly, the present study explored relations between adolescents’ preferences for mainstream and paraphilic pornography and their sexual satisfaction and sexual arousability in three-wave panel data using random intercept cross-lagged panel models. At a between-person level, only mainstream pornography viewing was positively related to adolescents’ sexual arousability. No relations were found between mainstream and paraphilic pornography viewing and sexual satisfaction at a between-person level. Results further revealed that an increased exposure to mainstream pornography and paraphilic pornography was not associated with sexual arousability and sexual satisfaction at the individual level. Null findings regarding paraphilic pornography viewing may be explained by the presence of a floor effect. Further, no differences in the investigated relations were found between sexually inexperienced and experienced adolescents, and between single adolescents and adolescents in a relationship. The findings are discussed in light of recent commentary on the uses of random-intercept cross-lagged panel models in the communication discipline.

Compulsive sexual behaviour in Iranian married women: Prevalence, sociodemographic, sexual, and psychological predictors across-country.

This study addresses the scarcity of research on Compulsive Sexual Behavior Disorder (CSBD) in non-Western cultures and women, exploring its prevalence, sociodemographic, sexual history characteristics, and sexual and psychological health factors in Iranian married women. A cross-sectional study involving 772 heterosexual married women was conducted between 2022 and 2023, covering all 31 provinces of Iran. Participants were categorized as CSBD+ (at-risk individuals) and CSBD- (low-risk individuals) based on a pre-established cut-off point of ≥18 by the Compulsive Sexual Behavior Disorder Scale -7. Depression, anxiety, obsessive-compulsive disorder, self-esteem, sexual distress, sexual satisfaction, relationship satisfaction, and sexual dysfunction were assessed as psychological and sexual health variables by standardized scales. The prevalence of CSBD was 3.8% in women. Linear regression analysis showed that lower education, being jobless, substance use, pornography use, paraphilic behaviors, conflict on sex frequency, relationship, orgasm and sexual dissatisfaction, higher sexual arousal, depression, and obsessive-compulsive symptoms were positively associated with CSBD. The univariate analysis, at a stringent significance level of 0.005, mirrored the regression findings. Additionally, women with CSBD+ exhibited lower religiousness and higher anxiety compared to those without CSBD-. Raising awareness of CSBD is crucial for health systems and individuals for better policy-making and help-seeking behavior. Identifying risk factors like substance use presents opportunities for prevention, and the association of CSBD with sexual and mental health variables suggests addressing co-occurring issues for improved treatment outcomes. Recognizing culture and gender-specific sexual and psychological correlates enables targeted and effective treatment approaches.

(O-06) PREVALENCE OF CLIMACTURIA IN POST RADICAL PROSTATECTOMY PATIENTS IN REFERRAL HOSPITAL IN BOGOTA

Abstract Introduction Climacturia is a frequent complication of radical prostatectomy (RP). Pelvic floor involvement and urinary sphincter functionality play a vital role in its pathophysiology. The prevalence in Colombia is unknown, and it is currently an underdiagnosed entity. This study aims to estimate the prevalence of climacturia in men undergoing RP in a fourth-level hospital in Bogota from 2018 to 2023. Methodology A descriptive cross-sectional observational study was conducted. Patients who attended postoperative control for 6 months and 1 year after a RP in the institution were included. A standardized survey was applied evaluating the presence of urine leakage during sexual arousal and/or orgasm and standardized scales of urinary incontinence and sexual function. Results Forty-four patients were included. The mean age of the patients was 64.7 (range: 45-81). The distribution of the surgical approach used in these patients is shown in Table 1. 56,8% (n=25) reported urine leakage during arousal. Of these patients, 43.1% (n=19) had received robot-assisted radical prostatectomy (RARP), followed by open surgery with 13,6% (n=6) of patients reporting this symptom. On the other hand, 38,6% (n=17) of patients had urine leakage during orgasm, of which the highest proportion of this symptom was open surgery. A limitation of the study was the lack of active search for this pathology in the general urological consultation and the poor response of patients to the forms. Conclusions The prevalence of climacturia is high and its diagnosis has multiple limitations. In addition, other post-prostatectomy side effects were identified, such as urine leakage with arousal, whose prevalence was higher than that of climacturia and may affect the sexuality of patients. Additionally, considering these are the preliminary findings from a prospective study, a larger sample size is required to achieve more representative results. Financing No conflict.